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J&J says its Covid vaccine booster shot generated a promising immune response in early trials

Johnson & Johnson mentioned Wednesday a booster shot of its Covid-19 vaccine generated a promising immune response in early stage medical trials – although the knowledge supplied by the corporate in a press launch was mild on some particulars.

J&J’s vaccine requires just one dose and recipients are thought of totally vaccinated two weeks after receiving the shot. The corporate mentioned Wednesday that J&J recipients who obtained a booster dose of the shot generated virus-fighting antibodies “nine-fold increased” than these seen 4 weeks after a single dose.

Will increase in antibody responses had been noticed in vaccine trial contributors between ages 18 and 55, the corporate mentioned, and in these 65 years and older who obtained a decrease dosage of the booster shot.

A person receives a shot of Johnson & Johnson Covid-19 vaccine at a pop-up vaccination middle on the seaside, in South Seashore, Florida, on Might 9, 2021.

Eva Marie Uzcategui | AFP | Getty Pictures

The outcomes are primarily based on two Section 1/2 research, in keeping with the corporate.

“We’ve got established {that a} single shot of our COVID-19 vaccine generates sturdy and sturdy immune responses which are sturdy and chronic via eight months,” Dr. Mathai Mammen, head of analysis and improvement at J&J’s Janssen vaccine arm, mentioned in a press release.

CNBC Well being & Science

“With these new knowledge, we additionally see {that a} booster dose of the Johnson & Johnson COVID-19 vaccine additional will increase antibody responses amongst research contributors who had beforehand obtained our vaccine,” he added.

Whereas the brand new knowledge is promising, the corporate’s press launch made no point out of the booster pictures’ potential influence on the coronavirus delta variant or on security.

When requested about knowledge on delta, J&J referred CNBC to a report in July that confirmed a single dose of the vaccine generated a promising immune response to the variant.

It additionally raises questions on why J&J recipients want booster pictures – particularly after the July report confirmed {that a} single shot of its vaccine supplies immunity that lasts at the least eight months and seems to ship satisfactory safety in opposition to the fast-spreading delta variant.

To make sure, the Facilities for Illness Management and Prevention has mentioned J&J recipients will most likely want a booster dose however added it would not have sufficient knowledge proper now to assist a proper advice.

The corporate mentioned Wednesday it’s partaking with the Meals and Drug Administration and different well being authorities relating to booster pictures.

The brand new knowledge comes lower than every week after J&J introduced that Alex Gorsky was stepping down as CEO. Gorsky, 61, who was chairman and CEO for 9 years, will turn into government chairman.


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